Deciphering the scopolamine challenge rat model by preclinical functional MRI
Abstract During preclinical drug testing, the systemic administration of scopolamine (SCO), a cholinergic antagonist, is widely used. However, it suffers important limitations, like non-specific behavioural effects partly due to its peripheral side-effects. Therefore, neuroimaging measures would enh...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/bc375befec4241b7a5e689a909becee5 |
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