Deciphering the scopolamine challenge rat model by preclinical functional MRI

Abstract During preclinical drug testing, the systemic administration of scopolamine (SCO), a cholinergic antagonist, is widely used. However, it suffers important limitations, like non-specific behavioural effects partly due to its peripheral side-effects. Therefore, neuroimaging measures would enh...

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Bibliographic Details
Main Authors: Gergely Somogyi, Dávid Hlatky, Tamás Spisák, Zsófia Spisák, Gabriella Nyitrai, András Czurkó
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/bc375befec4241b7a5e689a909becee5
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