Targeting <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Tumor Necrosis Factor Alpha-Downregulating Genes for the Development of Antituberculous Vaccines
ABSTRACT Tumor necrosis factor alpha (TNF) plays a critical role in the control of Mycobacterium tuberculosis, in part by augmenting T cell responses through promoting macrophage phagolysosomal fusion (thereby optimizing CD4+ T cell immunity by enhancing antigen presentation) and apoptosis (a proces...
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Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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American Society for Microbiology
2016
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Accès en ligne: | https://doaj.org/article/bc38b2b8f2174103a7ba8842d17365ec |
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