Transcriptional activity and strain-specific history of mouse pseudogenes

Pseudogenes are key markers of genome remodelling processes. Here the authors present genome-wide annotation of the pseudogenes in the mouse reference genome and 18 inbred mouse strains, update human pseudogene annotations, and characterise the transcription and evolution of mouse pseudogenes.

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Autores principales:	Cristina Sisu, Paul Muir, Adam Frankish, Ian Fiddes, Mark Diekhans, David Thybert, Duncan T. Odom, Paul Flicek, Thomas M. Keane, Tim Hubbard, Jennifer Harrow, Mark Gerstein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bc3bf2d1f24949899d576df8a558a91e
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spelling	oai:doaj.org-article:bc3bf2d1f24949899d576df8a558a91e2021-12-02T18:47:00ZTranscriptional activity and strain-specific history of mouse pseudogenes10.1038/s41467-020-17157-w2041-1723https://doaj.org/article/bc3bf2d1f24949899d576df8a558a91e2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17157-whttps://doaj.org/toc/2041-1723Pseudogenes are key markers of genome remodelling processes. Here the authors present genome-wide annotation of the pseudogenes in the mouse reference genome and 18 inbred mouse strains, update human pseudogene annotations, and characterise the transcription and evolution of mouse pseudogenes.Cristina SisuPaul MuirAdam FrankishIan FiddesMark DiekhansDavid ThybertDuncan T. OdomPaul FlicekThomas M. KeaneTim HubbardJennifer HarrowMark GersteinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cristina Sisu Paul Muir Adam Frankish Ian Fiddes Mark Diekhans David Thybert Duncan T. Odom Paul Flicek Thomas M. Keane Tim Hubbard Jennifer Harrow Mark Gerstein Transcriptional activity and strain-specific history of mouse pseudogenes
description	Pseudogenes are key markers of genome remodelling processes. Here the authors present genome-wide annotation of the pseudogenes in the mouse reference genome and 18 inbred mouse strains, update human pseudogene annotations, and characterise the transcription and evolution of mouse pseudogenes.
format	article
author	Cristina Sisu Paul Muir Adam Frankish Ian Fiddes Mark Diekhans David Thybert Duncan T. Odom Paul Flicek Thomas M. Keane Tim Hubbard Jennifer Harrow Mark Gerstein
author_facet	Cristina Sisu Paul Muir Adam Frankish Ian Fiddes Mark Diekhans David Thybert Duncan T. Odom Paul Flicek Thomas M. Keane Tim Hubbard Jennifer Harrow Mark Gerstein
author_sort	Cristina Sisu
title	Transcriptional activity and strain-specific history of mouse pseudogenes
title_short	Transcriptional activity and strain-specific history of mouse pseudogenes
title_full	Transcriptional activity and strain-specific history of mouse pseudogenes
title_fullStr	Transcriptional activity and strain-specific history of mouse pseudogenes
title_full_unstemmed	Transcriptional activity and strain-specific history of mouse pseudogenes
title_sort	transcriptional activity and strain-specific history of mouse pseudogenes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bc3bf2d1f24949899d576df8a558a91e
work_keys_str_mv	AT cristinasisu transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT paulmuir transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT adamfrankish transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT ianfiddes transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT markdiekhans transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT davidthybert transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT duncantodom transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT paulflicek transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT thomasmkeane transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT timhubbard transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT jenniferharrow transcriptionalactivityandstrainspecifichistoryofmousepseudogenes AT markgerstein transcriptionalactivityandstrainspecifichistoryofmousepseudogenes
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Transcriptional activity and strain-specific history of mouse pseudogenes

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