Progesterone alleviates neural behavioral deficits and demyelination with reduced degeneration of oligodendroglial cells in cuprizone-induced mice.
Demyelination occurs widely in neurodegenerative diseases. Progesterone has neuroprotective effects, is known to reduce the clinical scores and the inflammatory response. Progesterone also promotes remyelination in experimental autoimmune encephalomyelitis and cuprizone-induced demyelinating brain....
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Main Authors: | Jian-Ning Ye, Xing-Shu Chen, Le Su, Yun-Lai Liu, Qi-Yan Cai, Xiao-Li Zhan, Yan Xu, Shi-Fu Zhao, Zhong-Xiang Yao |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/bc470db32ecd4e84957bdd3e847e367c |
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