Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation
ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) is the first highly pathogenic human coronavirus to emerge since severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. Like many coronaviruses, MERS-CoV carries genes that encode multiple accessory proteins that are not req...
Saved in:
Main Authors: | Joshua M. Thornbrough, Babal K. Jha, Boyd Yount, Stephen A. Goldstein, Yize Li, Ruth Elliott, Amy C. Sims, Ralph S. Baric, Robert H. Silverman, Susan R. Weiss |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2016
|
Subjects: | |
Online Access: | https://doaj.org/article/bc4737fc08994557a29b4ee680bbd0de |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection
by: Courtney E. Comar, et al.
Published: (2019) -
Murine AKAP7 Has a 2′,5′-Phosphodiesterase Domain That Can Complement an Inactive Murine Coronavirus ns2 Gene
by: Elona Gusho, et al.
Published: (2014) -
Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis
by: Vineet D. Menachery, et al.
Published: (2017) -
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
by: S. J. Anthony, et al.
Published: (2017) -
Cell-Type-Specific Effects of RNase L on Viral Induction of Beta Interferon
by: Shuvojit Banerjee, et al.
Published: (2014)