Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes

S-palmitoylation regulation has been studied mostly in the cytosol and its role in mitochondria is unclear. Here the authors develop fluorescent mitochondria-targeted probes and find that depalmitoylation occurs in mitochondria and it’s influenced by alterations in mitochondrial lipid homeostasis.

Guardado en:
Detalles Bibliográficos
Autores principales: Rahul S. Kathayat, Yang Cao, Pablo D. Elvira, Patrick A. Sandoz, María-Eugenia Zaballa, Maya Z. Springer, Lauren E. Drake, Kay F. Macleod, F. Gisou van der Goot, Bryan C. Dickinson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/bc4834262d94405eb36f3f27406abe02
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!