Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes

S-palmitoylation regulation has been studied mostly in the cytosol and its role in mitochondria is unclear. Here the authors develop fluorescent mitochondria-targeted probes and find that depalmitoylation occurs in mitochondria and it’s influenced by alterations in mitochondrial lipid homeostasis.

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Autores principales:	Rahul S. Kathayat, Yang Cao, Pablo D. Elvira, Patrick A. Sandoz, María-Eugenia Zaballa, Maya Z. Springer, Lauren E. Drake, Kay F. Macleod, F. Gisou van der Goot, Bryan C. Dickinson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bc4834262d94405eb36f3f27406abe02
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spelling	oai:doaj.org-article:bc4834262d94405eb36f3f27406abe022021-12-02T17:31:46ZActive and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes10.1038/s41467-017-02655-12041-1723https://doaj.org/article/bc4834262d94405eb36f3f27406abe022018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02655-1https://doaj.org/toc/2041-1723S-palmitoylation regulation has been studied mostly in the cytosol and its role in mitochondria is unclear. Here the authors develop fluorescent mitochondria-targeted probes and find that depalmitoylation occurs in mitochondria and it’s influenced by alterations in mitochondrial lipid homeostasis.Rahul S. KathayatYang CaoPablo D. ElviraPatrick A. SandozMaría-Eugenia ZaballaMaya Z. SpringerLauren E. DrakeKay F. MacleodF. Gisou van der GootBryan C. DickinsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rahul S. Kathayat Yang Cao Pablo D. Elvira Patrick A. Sandoz María-Eugenia Zaballa Maya Z. Springer Lauren E. Drake Kay F. Macleod F. Gisou van der Goot Bryan C. Dickinson Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
description	S-palmitoylation regulation has been studied mostly in the cytosol and its role in mitochondria is unclear. Here the authors develop fluorescent mitochondria-targeted probes and find that depalmitoylation occurs in mitochondria and it’s influenced by alterations in mitochondrial lipid homeostasis.
format	article
author	Rahul S. Kathayat Yang Cao Pablo D. Elvira Patrick A. Sandoz María-Eugenia Zaballa Maya Z. Springer Lauren E. Drake Kay F. Macleod F. Gisou van der Goot Bryan C. Dickinson
author_facet	Rahul S. Kathayat Yang Cao Pablo D. Elvira Patrick A. Sandoz María-Eugenia Zaballa Maya Z. Springer Lauren E. Drake Kay F. Macleod F. Gisou van der Goot Bryan C. Dickinson
author_sort	Rahul S. Kathayat
title	Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
title_short	Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
title_full	Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
title_fullStr	Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
title_full_unstemmed	Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
title_sort	active and dynamic mitochondrial s-depalmitoylation revealed by targeted fluorescent probes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bc4834262d94405eb36f3f27406abe02
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Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes

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