Sclerostin and Its Involvement in the Pathogenesis of Idiopathic Scoliosis

Idiopathic scoliosis is a disorder of unknown etiology. Bone biopsies from idiopathic scoliosis patients revealed changes at cellular and molecular level. Osteocytic sclerostin is downregulated, and serum level of sclerostin is decreased. Osteocytes in idiopathic scoliosis appear to be less active w...

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Autores principales: Elias S. Vasiliadis, Dimitrios Stergios Evangelopoulos, Angelos Kaspiris, Christos Vlachos, Spyros G. Pneumaticos
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/bc55d6f9420944c9b327bd16794d7814
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