GluN2A and GluN2B NMDA receptors use distinct allosteric routes

NMDA receptors are glutamate-gated ion channels essential for synapse maturation and plasticity. Here the authors show that GluN2A and GluN2B NMDA receptors — the two principal subtypes NMDARs in the adult CNS — operate through distinct long range allosteric mechanisms.

Guardado en:
Detalles Bibliográficos
Autores principales: Meilin Tian, David Stroebel, Laura Piot, Mélissa David, Shixin Ye, Pierre Paoletti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/bc578a7cc0a845ae800db6cf37ab3c40
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!