GluN2A and GluN2B NMDA receptors use distinct allosteric routes
NMDA receptors are glutamate-gated ion channels essential for synapse maturation and plasticity. Here the authors show that GluN2A and GluN2B NMDA receptors — the two principal subtypes NMDARs in the adult CNS — operate through distinct long range allosteric mechanisms.
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Autores principales: | Meilin Tian, David Stroebel, Laura Piot, Mélissa David, Shixin Ye, Pierre Paoletti |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bc578a7cc0a845ae800db6cf37ab3c40 |
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