The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement.

Translational control and messenger RNA (mRNA) decay represent important control points in the regulation of gene expression. In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by decapping and 5'-3' exonucleolytic digestion of the mRNA. Proteins that activat...

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Auteurs principaux: Thomas Sweet, Carrie Kovalak, Jeff Coller
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/bc893de7687542c5a6e1098188b678ce
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