Evaluation of excess significance bias in animal studies of neurological diseases.

Animal studies generate valuable hypotheses that lead to the conduct of preventive or therapeutic clinical trials. We assessed whether there is evidence for excess statistical significance in results of animal studies on neurological disorders, suggesting biases. We used data from meta-analyses of i...

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Autores principales: Konstantinos K Tsilidis, Orestis A Panagiotou, Emily S Sena, Eleni Aretouli, Evangelos Evangelou, David W Howells, Rustam Al-Shahi Salman, Malcolm R Macleod, John P A Ioannidis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/bca865a5a5cf43c1bf8387fb018d8c16
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