Pathway-based subnetworks enable cross-disease biomarker discovery

Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.

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Autores principales: Syed Haider, Cindy Q. Yao, Vicky S. Sabine, Michal Grzadkowski, Vincent Stimper, Maud H. W. Starmans, Jianxin Wang, Francis Nguyen, Nathalie C. Moon, Xihui Lin, Camilla Drake, Cheryl A. Crozier, Cassandra L. Brookes, Cornelis J. H. van de Velde, Annette Hasenburg, Dirk G. Kieback, Christos J. Markopoulos, Luc Y. Dirix, Caroline Seynaeve, Daniel W. Rea, Arek Kasprzyk, Philippe Lambin, Pietro Lio’, John M. S. Bartlett, Paul C. Boutros
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/bcb37461217c4cbca56503d084f11052
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