Pathway-based subnetworks enable cross-disease biomarker discovery
Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/bcb37461217c4cbca56503d084f11052 |
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oai:doaj.org-article:bcb37461217c4cbca56503d084f110522021-12-02T17:32:00ZPathway-based subnetworks enable cross-disease biomarker discovery10.1038/s41467-018-07021-32041-1723https://doaj.org/article/bcb37461217c4cbca56503d084f110522018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07021-3https://doaj.org/toc/2041-1723Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.Syed HaiderCindy Q. YaoVicky S. SabineMichal GrzadkowskiVincent StimperMaud H. W. StarmansJianxin WangFrancis NguyenNathalie C. MoonXihui LinCamilla DrakeCheryl A. CrozierCassandra L. BrookesCornelis J. H. van de VeldeAnnette HasenburgDirk G. KiebackChristos J. MarkopoulosLuc Y. DirixCaroline SeynaeveDaniel W. ReaArek KasprzykPhilippe LambinPietro Lio’John M. S. BartlettPaul C. BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Syed Haider Cindy Q. Yao Vicky S. Sabine Michal Grzadkowski Vincent Stimper Maud H. W. Starmans Jianxin Wang Francis Nguyen Nathalie C. Moon Xihui Lin Camilla Drake Cheryl A. Crozier Cassandra L. Brookes Cornelis J. H. van de Velde Annette Hasenburg Dirk G. Kieback Christos J. Markopoulos Luc Y. Dirix Caroline Seynaeve Daniel W. Rea Arek Kasprzyk Philippe Lambin Pietro Lio’ John M. S. Bartlett Paul C. Boutros Pathway-based subnetworks enable cross-disease biomarker discovery |
description |
Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery. |
format |
article |
author |
Syed Haider Cindy Q. Yao Vicky S. Sabine Michal Grzadkowski Vincent Stimper Maud H. W. Starmans Jianxin Wang Francis Nguyen Nathalie C. Moon Xihui Lin Camilla Drake Cheryl A. Crozier Cassandra L. Brookes Cornelis J. H. van de Velde Annette Hasenburg Dirk G. Kieback Christos J. Markopoulos Luc Y. Dirix Caroline Seynaeve Daniel W. Rea Arek Kasprzyk Philippe Lambin Pietro Lio’ John M. S. Bartlett Paul C. Boutros |
author_facet |
Syed Haider Cindy Q. Yao Vicky S. Sabine Michal Grzadkowski Vincent Stimper Maud H. W. Starmans Jianxin Wang Francis Nguyen Nathalie C. Moon Xihui Lin Camilla Drake Cheryl A. Crozier Cassandra L. Brookes Cornelis J. H. van de Velde Annette Hasenburg Dirk G. Kieback Christos J. Markopoulos Luc Y. Dirix Caroline Seynaeve Daniel W. Rea Arek Kasprzyk Philippe Lambin Pietro Lio’ John M. S. Bartlett Paul C. Boutros |
author_sort |
Syed Haider |
title |
Pathway-based subnetworks enable cross-disease biomarker discovery |
title_short |
Pathway-based subnetworks enable cross-disease biomarker discovery |
title_full |
Pathway-based subnetworks enable cross-disease biomarker discovery |
title_fullStr |
Pathway-based subnetworks enable cross-disease biomarker discovery |
title_full_unstemmed |
Pathway-based subnetworks enable cross-disease biomarker discovery |
title_sort |
pathway-based subnetworks enable cross-disease biomarker discovery |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/bcb37461217c4cbca56503d084f11052 |
work_keys_str_mv |
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