Pathway-based subnetworks enable cross-disease biomarker discovery

Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.

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Autores principales: Syed Haider, Cindy Q. Yao, Vicky S. Sabine, Michal Grzadkowski, Vincent Stimper, Maud H. W. Starmans, Jianxin Wang, Francis Nguyen, Nathalie C. Moon, Xihui Lin, Camilla Drake, Cheryl A. Crozier, Cassandra L. Brookes, Cornelis J. H. van de Velde, Annette Hasenburg, Dirk G. Kieback, Christos J. Markopoulos, Luc Y. Dirix, Caroline Seynaeve, Daniel W. Rea, Arek Kasprzyk, Philippe Lambin, Pietro Lio’, John M. S. Bartlett, Paul C. Boutros
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/bcb37461217c4cbca56503d084f11052
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spelling oai:doaj.org-article:bcb37461217c4cbca56503d084f110522021-12-02T17:32:00ZPathway-based subnetworks enable cross-disease biomarker discovery10.1038/s41467-018-07021-32041-1723https://doaj.org/article/bcb37461217c4cbca56503d084f110522018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07021-3https://doaj.org/toc/2041-1723Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.Syed HaiderCindy Q. YaoVicky S. SabineMichal GrzadkowskiVincent StimperMaud H. W. StarmansJianxin WangFrancis NguyenNathalie C. MoonXihui LinCamilla DrakeCheryl A. CrozierCassandra L. BrookesCornelis J. H. van de VeldeAnnette HasenburgDirk G. KiebackChristos J. MarkopoulosLuc Y. DirixCaroline SeynaeveDaniel W. ReaArek KasprzykPhilippe LambinPietro Lio’John M. S. BartlettPaul C. BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Syed Haider
Cindy Q. Yao
Vicky S. Sabine
Michal Grzadkowski
Vincent Stimper
Maud H. W. Starmans
Jianxin Wang
Francis Nguyen
Nathalie C. Moon
Xihui Lin
Camilla Drake
Cheryl A. Crozier
Cassandra L. Brookes
Cornelis J. H. van de Velde
Annette Hasenburg
Dirk G. Kieback
Christos J. Markopoulos
Luc Y. Dirix
Caroline Seynaeve
Daniel W. Rea
Arek Kasprzyk
Philippe Lambin
Pietro Lio’
John M. S. Bartlett
Paul C. Boutros
Pathway-based subnetworks enable cross-disease biomarker discovery
description Accurate and actionable biomarkers that integrate diverse molecular, functional and clinical information hold great promise in precision medicine. Here, the authors develop SIMMS, a method for pathway-based cross-disease biomarker discovery.
format article
author Syed Haider
Cindy Q. Yao
Vicky S. Sabine
Michal Grzadkowski
Vincent Stimper
Maud H. W. Starmans
Jianxin Wang
Francis Nguyen
Nathalie C. Moon
Xihui Lin
Camilla Drake
Cheryl A. Crozier
Cassandra L. Brookes
Cornelis J. H. van de Velde
Annette Hasenburg
Dirk G. Kieback
Christos J. Markopoulos
Luc Y. Dirix
Caroline Seynaeve
Daniel W. Rea
Arek Kasprzyk
Philippe Lambin
Pietro Lio’
John M. S. Bartlett
Paul C. Boutros
author_facet Syed Haider
Cindy Q. Yao
Vicky S. Sabine
Michal Grzadkowski
Vincent Stimper
Maud H. W. Starmans
Jianxin Wang
Francis Nguyen
Nathalie C. Moon
Xihui Lin
Camilla Drake
Cheryl A. Crozier
Cassandra L. Brookes
Cornelis J. H. van de Velde
Annette Hasenburg
Dirk G. Kieback
Christos J. Markopoulos
Luc Y. Dirix
Caroline Seynaeve
Daniel W. Rea
Arek Kasprzyk
Philippe Lambin
Pietro Lio’
John M. S. Bartlett
Paul C. Boutros
author_sort Syed Haider
title Pathway-based subnetworks enable cross-disease biomarker discovery
title_short Pathway-based subnetworks enable cross-disease biomarker discovery
title_full Pathway-based subnetworks enable cross-disease biomarker discovery
title_fullStr Pathway-based subnetworks enable cross-disease biomarker discovery
title_full_unstemmed Pathway-based subnetworks enable cross-disease biomarker discovery
title_sort pathway-based subnetworks enable cross-disease biomarker discovery
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/bcb37461217c4cbca56503d084f11052
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