CD4<sup>+</sup> T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy

ABSTRACT Therapeutic strategies that provide effective and broad‐spectrum neutralization against HIV-1 infection are highly desirable. Here, we investigate the potential of nanoengineered CD4+ T cell membrane-coated nanoparticles (TNP) to neutralize a broad range of HIV-1 strains. TNP displayed outs...

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Autores principales: Gang Zhang, Grant R. Campbell, Qiangzhe Zhang, Erin Maule, Jonathan Hanna, Weiwei Gao, Liangfang Zhang, Stephen A. Spector
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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HIV
Acceso en línea:https://doaj.org/article/bcd1ffecf9ad42c095dd956fce43381e
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