Assembling custom side chains on proteoglycans to interrogate their function in living cells

Currently, it is not possible to generate proteoglycans displaying glycosaminoglycan chains with specific structures. Here the authors show that by using an aldehyde tag-based methodology it is possible to insert these specific chains onto proteoglycans expressed on the cell surface.

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Autores principales: Wenshuang Wang, Naihan Han, Yingying Xu, Yunxue Zhao, Liran Shi, Jorge Filmus, Fuchuan Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bd135f511def4709b023984758718989
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