Gene variants and expression changes of SIRT1 and SIRT6 in peripheral blood are associated with Parkinson’s disease
Abstract Parkinson’s disease (PD) is a neurodegenerative disease caused by complex interaction between genetic and environmental factors. There is a growing body of evidence of the involvement of sirtuins (SIRTs) in disease pathomechanism. SIRTs are NAD+-dependent histone deacetylases which take par...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bd1d6dc5b0e846eaad15fa28334ded90 |
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