Identification of novel functional inhibitors of acid sphingomyelinase.

Identification of novel functional inhibitors of acid sphingomyelinase.

We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibition of acid sphingomyelinase (ASM). These entities named FIASMAs (Functional Inhibitors of Acid SphingoMyelinAse), therefore, can be potentially used to treat diseases associated with enhanced activity...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Johannes Kornhuber, Markus Muehlbacher, Stefan Trapp, Stefanie Pechmann, Astrid Friedl, Martin Reichel, Christiane Mühle, Lothar Terfloth, Teja W Groemer, Gudrun M Spitzer, Klaus R Liedl, Erich Gulbins, Philipp Tripal
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/bd25bf066ec3473fbd19d8571dd669db
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/bd25bf066ec3473fbd19d8571dd669db

Documents similaires