Improving the Precision of Base Editing by Bubble Hairpin Single Guide RNA
Base editors are double-strand-break (DSB)-free genome editing tools and have been widely used in diverse living systems. However, it is reported that these tools can cause substantial off-target editing.
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bdac9787d38e4570b75d966420a1da21 |
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Sumario: | Base editors are double-strand-break (DSB)-free genome editing tools and have been widely used in diverse living systems. However, it is reported that these tools can cause substantial off-target editing. |
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