Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions
Most approaches to control gene expression in vivo require generation of knock-in mouse lines and often lack spatiotemporal control. Here the authors develop a photo-activatable Flp recombinase system and demonstrate its use by controlling object-exploration behavior in mice through Cav3.1 silencing...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/bdb35816507e4ab195f71dcd83e79b7e |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|