Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Blood metabolite levels are under the influence of environmental and genetic factors. Here, Hagenbeek et al. perform heritability estimations for metabolite measures and determine the contribution of known metabolite loci to metabolite levels using data from 40 genome-wide association studies.

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Autores principales:	Fiona A. Hagenbeek, René Pool, Jenny van Dongen, Harmen H. M. Draisma, Jouke Jan Hottenga, Gonneke Willemsen, Abdel Abdellaoui, Iryna O. Fedko, Anouk den Braber, Pieter Jelle Visser, Eco J. C. N. de Geus, Ko Willems van Dijk, Aswin Verhoeven, H. Eka Suchiman, Marian Beekman, P. Eline Slagboom, Cornelia M. van Duijn, BBMRI Metabolomics Consortium, Amy C. Harms, Thomas Hankemeier, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bdd7a85c5d32461f9a054623f04904bd
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spelling	oai:doaj.org-article:bdd7a85c5d32461f9a054623f04904bd2021-12-02T17:31:25ZHeritability estimates for 361 blood metabolites across 40 genome-wide association studies10.1038/s41467-019-13770-62041-1723https://doaj.org/article/bdd7a85c5d32461f9a054623f04904bd2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13770-6https://doaj.org/toc/2041-1723Blood metabolite levels are under the influence of environmental and genetic factors. Here, Hagenbeek et al. perform heritability estimations for metabolite measures and determine the contribution of known metabolite loci to metabolite levels using data from 40 genome-wide association studies.Fiona A. HagenbeekRené PoolJenny van DongenHarmen H. M. DraismaJouke Jan HottengaGonneke WillemsenAbdel AbdellaouiIryna O. FedkoAnouk den BraberPieter Jelle VisserEco J. C. N. de GeusKo Willems van DijkAswin VerhoevenH. Eka SuchimanMarian BeekmanP. Eline SlagboomCornelia M. van DuijnBBMRI Metabolomics ConsortiumAmy C. HarmsThomas HankemeierMeike BartelsMichel G. NivardDorret I. BoomsmaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fiona A. Hagenbeek René Pool Jenny van Dongen Harmen H. M. Draisma Jouke Jan Hottenga Gonneke Willemsen Abdel Abdellaoui Iryna O. Fedko Anouk den Braber Pieter Jelle Visser Eco J. C. N. de Geus Ko Willems van Dijk Aswin Verhoeven H. Eka Suchiman Marian Beekman P. Eline Slagboom Cornelia M. van Duijn BBMRI Metabolomics Consortium Amy C. Harms Thomas Hankemeier Meike Bartels Michel G. Nivard Dorret I. Boomsma Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
description	Blood metabolite levels are under the influence of environmental and genetic factors. Here, Hagenbeek et al. perform heritability estimations for metabolite measures and determine the contribution of known metabolite loci to metabolite levels using data from 40 genome-wide association studies.
format	article
author	Fiona A. Hagenbeek René Pool Jenny van Dongen Harmen H. M. Draisma Jouke Jan Hottenga Gonneke Willemsen Abdel Abdellaoui Iryna O. Fedko Anouk den Braber Pieter Jelle Visser Eco J. C. N. de Geus Ko Willems van Dijk Aswin Verhoeven H. Eka Suchiman Marian Beekman P. Eline Slagboom Cornelia M. van Duijn BBMRI Metabolomics Consortium Amy C. Harms Thomas Hankemeier Meike Bartels Michel G. Nivard Dorret I. Boomsma
author_facet	Fiona A. Hagenbeek René Pool Jenny van Dongen Harmen H. M. Draisma Jouke Jan Hottenga Gonneke Willemsen Abdel Abdellaoui Iryna O. Fedko Anouk den Braber Pieter Jelle Visser Eco J. C. N. de Geus Ko Willems van Dijk Aswin Verhoeven H. Eka Suchiman Marian Beekman P. Eline Slagboom Cornelia M. van Duijn BBMRI Metabolomics Consortium Amy C. Harms Thomas Hankemeier Meike Bartels Michel G. Nivard Dorret I. Boomsma
author_sort	Fiona A. Hagenbeek
title	Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
title_short	Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
title_full	Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
title_fullStr	Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
title_full_unstemmed	Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
title_sort	heritability estimates for 361 blood metabolites across 40 genome-wide association studies
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bdd7a85c5d32461f9a054623f04904bd
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Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

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