Mixed <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Peptide Antigens Provide a Specific and Sensitive Single-Well Colorimetric Enzyme-Linked Immunosorbent Assay for Detection of Human Anti<italic toggle="yes">-</italic><named-content content-type="genus-species">C. trachomatis</named-content> Antibodies

Mixed <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Peptide Antigens Provide a Specific and Sensitive Single-Well Colorimetric Enzyme-Linked Immunosorbent Assay for Detection of Human Anti<italic toggle="yes">-</italic><named-content content-type="genus-species">C. trachomatis</named-content> Antibodies

ABSTRACT Sensitive and specific detection of anti-Chlamydia trachomatis antibodies in standard enzyme-linked immunosorbent assays (ELISAs) is compromised by cross-reactivity and poor sensitivity of classical C. trachomatis antigens. Previously, we discovered 48 strongly reactive peptide antigens of...

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Bibliographic Details
Main Authors: K. Shamsur Rahman, Toni Darville, Harold C. Wiesenfeld, Sharon L. Hillier, Bernhard Kaltenboeck
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Chlamydia trachomatis
diagnosis
serology
antibody detection
B-cell epitopes
peptide antigens
Microbiology
QR1-502
Online Access:https://doaj.org/article/bde4bf478e634931aed877ccc8db5c14
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https://doaj.org/article/bde4bf478e634931aed877ccc8db5c14

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