IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation

IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation

Clearance of apoptotic neutrophils by macrophages is important for the resolution of inflammation. Here, the authors show that interferon-β produced by resolution phase macrophages promotes neutrophil apoptosis and efferocytosis and induces macrophage reprogramming to a pro-resolving phenotype, ther...

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Main Authors: Senthil Kumaran Satyanarayanan, Driss El Kebir, Soaad Soboh, Sergei Butenko, Meriem Sekheri, Janan Saadi, Neta Peled, Simaan Assi, Amira Othman, Sagie Schif-Zuck, Yonatan Feuermann, Dalit Barkan, Noa Sher, János G. Filep, Amiram Ariel
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/bde7b79a24f74c988fe97e64005be189
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https://doaj.org/article/bde7b79a24f74c988fe97e64005be189

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