Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis.
We consider the problem of how to detect cognate pairs of proteins that bind when each belongs to a large family of paralogs. To illustrate the problem, we have undertaken a genomewide analysis of interactions of members of the PE and PPE protein families of Mycobacterium tuberculosis. Our computati...
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Auteurs principaux: | , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2008
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Accès en ligne: | https://doaj.org/article/bdfa560007144321b68048f6ed7fcb54 |
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