Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.

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Detalles Bibliográficos
Autores principales: Zhao Zhang, Joo-Hyung Lee, Hang Ruan, Youqiong Ye, Joanna Krakowiak, Qingsong Hu, Yu Xiang, Jing Gong, Bingying Zhou, Li Wang, Chunru Lin, Lixia Diao, Gordon B. Mills, Wenbo Li, Leng Han
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/be0580705883405e8211bdfc3cb55317
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Descripción
Sumario:Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.