Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.

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Autores principales:	Zhao Zhang, Joo-Hyung Lee, Hang Ruan, Youqiong Ye, Joanna Krakowiak, Qingsong Hu, Yu Xiang, Jing Gong, Bingying Zhou, Li Wang, Chunru Lin, Lixia Diao, Gordon B. Mills, Wenbo Li, Leng Han
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be0580705883405e8211bdfc3cb55317
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spelling	oai:doaj.org-article:be0580705883405e8211bdfc3cb553172021-12-02T14:39:42ZTranscriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer10.1038/s41467-019-12543-52041-1723https://doaj.org/article/be0580705883405e8211bdfc3cb553172019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12543-5https://doaj.org/toc/2041-1723Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.Zhao ZhangJoo-Hyung LeeHang RuanYouqiong YeJoanna KrakowiakQingsong HuYu XiangJing GongBingying ZhouLi WangChunru LinLixia DiaoGordon B. MillsWenbo LiLeng HanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhao Zhang Joo-Hyung Lee Hang Ruan Youqiong Ye Joanna Krakowiak Qingsong Hu Yu Xiang Jing Gong Bingying Zhou Li Wang Chunru Lin Lixia Diao Gordon B. Mills Wenbo Li Leng Han Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
description	Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from enhancer regions. Here, the authors investigate the transcriptional landscape of eRNA in cancer, incorporating pharmacogenomic data to identify potential target genes and therapeutic targets.
format	article
author	Zhao Zhang Joo-Hyung Lee Hang Ruan Youqiong Ye Joanna Krakowiak Qingsong Hu Yu Xiang Jing Gong Bingying Zhou Li Wang Chunru Lin Lixia Diao Gordon B. Mills Wenbo Li Leng Han
author_facet	Zhao Zhang Joo-Hyung Lee Hang Ruan Youqiong Ye Joanna Krakowiak Qingsong Hu Yu Xiang Jing Gong Bingying Zhou Li Wang Chunru Lin Lixia Diao Gordon B. Mills Wenbo Li Leng Han
author_sort	Zhao Zhang
title	Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
title_short	Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
title_full	Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
title_fullStr	Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
title_full_unstemmed	Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer
title_sort	transcriptional landscape and clinical utility of enhancer rnas for erna-targeted therapy in cancer
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/be0580705883405e8211bdfc3cb55317
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Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

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