Mutations in LMNA modulate the lamin A--Nesprin-2 interaction and cause LINC complex alterations.
<h4>Background</h4>In eukaryotes the genetic material is enclosed by a continuous membrane system, the nuclear envelope (NE). Along the NE specific proteins assemble to form meshworks and mutations in these proteins have been described in a group of human diseases called laminopathies. L...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Acceso en línea: | https://doaj.org/article/be5a7a7122af45e9837089214e80377f |
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