Genome scale patterns of supercoiling in a bacterial chromosome

Bacterial DNA primarily exists in a negatively supercoiled or under-wound state. Here, by mapping the supercoiling state, the authors show that there is a gradient of supercoiling across the bacterial chromosome with the terminus being more negatively supercoiled than the origin.

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Auteurs principaux: Avantika Lal, Amlanjyoti Dhar, Andrei Trostel, Fedor Kouzine, Aswin S. N. Seshasayee, Sankar Adhya
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
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Accès en ligne:https://doaj.org/article/be7611785c574ff2bbac48aeae9ad064
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