Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death
Abstract Pro-inflammatory cytokines are important mediators of islet inflammation, leading to beta cell death in type 1 diabetes. Although alterations in both endoplasmic reticulum (ER) and cytosolic free calcium levels are known to play a role in cytokine-mediated beta cell death, there are current...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/be8e2bac311c4815b5a158b712b3a6a3 |
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