Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations.
<h4>Background</h4>In human embryogenesis, loss of SRY (sex determining region on Y), SOX9 (SRY-related HMG box 9) or SF1 (steroidogenic factor 1) function causes disorders of sex development (DSD). A defining event of vertebrate sex determination is male-specific upregulation and mainte...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2011
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| Subjects: | |
| Online Access: | https://doaj.org/article/bea90a38f7f8408cb1c98344a5605be2 |
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