Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells.

Transient cell therapy is an emerging drug class that requires new approaches for pharmacological monitoring during use. Human mesenchymal stem cells (MSCs) are a clinically-tested transient cell therapeutic that naturally secrete anti-inflammatory factors to attenuate immune-mediated diseases. MSCs...

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Auteurs principaux: Jessica S Elman, Ryan C Murray, Fangjing Wang, Keyue Shen, Shan Gao, Kevin E Conway, Martin L Yarmush, Bakhos A Tannous, Ralph Weissleder, Biju Parekkadan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/bebf5db53a4d4a56accd59d2bbe8606b
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