Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers

Mass-spectrometry-based profiling can be used to stratify tumours into molecular subtypes. Here, by classifying over 500 tumours, the authors show that this approach reveals proteomic subgroups which cut across tumour types.

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Autores principales:	Fengju Chen, Darshan S. Chandrashekar, Sooryanarayana Varambally, Chad J. Creighton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bedcde693ec34da7b8d8594c194d689d
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spelling	oai:doaj.org-article:bedcde693ec34da7b8d8594c194d689d2021-12-02T17:33:24ZPan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers10.1038/s41467-019-13528-02041-1723https://doaj.org/article/bedcde693ec34da7b8d8594c194d689d2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13528-0https://doaj.org/toc/2041-1723Mass-spectrometry-based profiling can be used to stratify tumours into molecular subtypes. Here, by classifying over 500 tumours, the authors show that this approach reveals proteomic subgroups which cut across tumour types.Fengju ChenDarshan S. ChandrashekarSooryanarayana VaramballyChad J. CreightonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fengju Chen Darshan S. Chandrashekar Sooryanarayana Varambally Chad J. Creighton Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
description	Mass-spectrometry-based profiling can be used to stratify tumours into molecular subtypes. Here, by classifying over 500 tumours, the authors show that this approach reveals proteomic subgroups which cut across tumour types.
format	article
author	Fengju Chen Darshan S. Chandrashekar Sooryanarayana Varambally Chad J. Creighton
author_facet	Fengju Chen Darshan S. Chandrashekar Sooryanarayana Varambally Chad J. Creighton
author_sort	Fengju Chen
title	Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
title_short	Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
title_full	Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
title_fullStr	Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
title_full_unstemmed	Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
title_sort	pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bedcde693ec34da7b8d8594c194d689d
work_keys_str_mv	AT fengjuchen pancancermolecularsubtypesrevealedbymassspectrometrybasedproteomiccharacterizationofmorethan500humancancers AT darshanschandrashekar pancancermolecularsubtypesrevealedbymassspectrometrybasedproteomiccharacterizationofmorethan500humancancers AT sooryanarayanavarambally pancancermolecularsubtypesrevealedbymassspectrometrybasedproteomiccharacterizationofmorethan500humancancers AT chadjcreighton pancancermolecularsubtypesrevealedbymassspectrometrybasedproteomiccharacterizationofmorethan500humancancers
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Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers

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