The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane

ABSTRACT All enveloped viruses, including herpesviruses, must fuse their envelope with the host membrane to deliver their genomes into target cells, making this essential step subject to interference by antibodies and drugs. Viral fusion is mediated by a viral surface protein that transits from an i...

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Autores principales: Juan Fontana, Doina Atanasiu, Wan Ting Saw, John R. Gallagher, Reagan G. Cox, J. Charles Whitbeck, Lauren M. Brown, Roselyn J. Eisenberg, Gary H. Cohen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
HSV
gB
Acceso en línea:https://doaj.org/article/bedf0d56e13a4379a5a712758525c86a
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