Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence of <named-content content-type="genus-species">Streptococcus pyogenes</named-content>
ABSTRACT Serum opacity factor (SOF) is a cell surface virulence factor made by the human pathogen Streptococcus pyogenes. We found that S. pyogenes strains with naturally occurring truncation mutations in the sof gene have markedly enhanced beta-hemolysis. Moreover, deletion of the sof gene in a SOF...
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Main Authors: | Luchang Zhu, Randall J. Olsen, James M. Musser |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Online Access: | https://doaj.org/article/beeeb39dcb5b4ce9a158a3854f9701b7 |
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