Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells.

Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells.

<h4>Background</h4>Lamins are structural proteins that are the major determinants of nuclear architecture and play important roles in various nuclear functions including gene regulation and cell differentiation. Mutations in the human lamin A gene cause a spectrum of genetic diseases tha...

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Bibliographic Details
Main Authors: Poonam Sehgal, Pankaj Chaturvedi, R Ileng Kumaran, Satish Kumar, Veena K Parnaik
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/befc04be16b1439f8f40ea40c92beaa3
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