Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort

Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort

Aims: Despite the interest in the association of gut microbiota with bone health, limited population-based studies of gut microbiota and bone mineral density (BMD) have been made. Our aim is to explore the possible association between gut microbiota and BMD. Methods: A total of 3,321 independent loc...

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Bibliographic Details
Main Authors: Bolun Cheng, Yan Wen, Xuena Yang, Shiqiang Cheng, Li Liu, Xiaomeng Chu, Jing Ye, Chujun Liang, Yao Yao, Yumeng Jia, Feng Zhang
Format: article
Language:EN
Published: The British Editorial Society of Bone & Joint Surgery 2021
Subjects:
gut microbiota
bone mineral density
polygenic risk score
bone mineral density (bmd)
femur
single-nucleotide polymorphisms (snps)
linear regression models
osteoporosis
osteoblasts
bone formation
macrophages
bone density loss
bone metabolism
Diseases of the musculoskeletal system
RC925-935
Online Access:https://doaj.org/article/bf0bdb2e849c413cb25b64bfaa0e07a4
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