FGF23 deficiency leads to mixed hearing loss and middle ear malformation in mice.

Fibroblast growth factor 23 (FGF23) is a circulating hormone important in phosphate homeostasis. Abnormal serum levels of FGF23 result in systemic pathologies in humans and mice, including renal phosphate wasting diseases and hyperphosphatemia. We sought to uncover the role FGF23 plays in the audito...

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Auteurs principaux: Andrew C Lysaght, Quan Yuan, Yi Fan, Neil Kalwani, Paul Caruso, MaryBeth Cunnane, Beate Lanske, Konstantina M Stanković
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/bf0e45ea0da74dad906e54f2eefd8c43
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