HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.

HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.

<h4>Background</h4>Although recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) gene is highly expressed in hES...

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Bibliographic Details
Main Authors: Sandeep N Shah, Candace Kerr, Leslie Cope, Elias Zambidis, Cyndi Liu, Joelle Hillion, Amy Belton, David L Huso, Linda M S Resar
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/bf1d8137a917472cac9e7e1d97cda020
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