Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

NEMO is a member of the IKK complex that binds ubiquitin, involved in NF-κB signalling and proposed to form higher order structures. Here the authors use super-resolution microscopy to detect the presence of NEMO lattices in cells, that are modified by NF-κB treatment and abrogated by mutations affe...

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Bibliographic Details
Main Authors: Janine Scholefield, Ricardo Henriques, Anca F. Savulescu, Elisabeth Fontan, Alix Boucharlat, Emmanuel Laplantine, Asma Smahi, Alain Israël, Fabrice Agou, Musa M. Mhlanga
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/bf1e75c472b84f6aaf2453cc4cab9d72
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