Cytochrome P450 3A1 mediates 2,2',4,4'-tetrabromodiphenyl ether-induced reduction of spermatogenesis in adult rats.

<h4>Background</h4>2,2',4,4'-tetrabromodiphenyl ether (BDE47) is the dominant PBDE congener in humans, wildlife, and the environment. It has been reported to be metabolized by cytochrome P450 (CYP) enzymes. Still, the effects of BDE47 on spermatogenesis failure are attracting a...

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Autores principales: Zhan Zhang, Xiaoming Zhang, Zhenzhen Sun, Huibin Dong, Lianglin Qiu, Jun Gu, Jingping Zhou, Xinru Wang, Shou-Lin Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/bf2762ef527c48dbb20b9ad6c7130548
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