Inhibition of Wnt signaling pathway suppresses radiation-induced dermal fibrosis

Abstract Progressive fibrosis of the dermal tissues is a challenging complication of radiotherapy whose underlying mechanism is not fully understood, and there are few available treatments. The canonical Wnt/β-catenin signaling pathway plays an important role in fibrosis as well as in the epithelial...

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Autores principales: Dong Won Lee, Won Jai Lee, Jaeho Cho, Chae-Ok Yun, Hyun Roh, Hsien Pin Chang, Tai Suk Roh, Ju Hee Lee, Dae Hyun Lew
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bf3f13052af349e892ead6c07108c6c5
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