Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50
Abstract BRCA1 associated ring domain protein 1(BARD1) is a tumor suppressor protein having a wide role in cellular processes like cell-cycle checkpoint, DNA damage repair and maintenance of genomic integrity. Germ-line mutation Gln 564 His discovered in linker region of BARD1 leads to loss of bindi...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/bf40bf00aad3482ab15109c7ad448f44 |
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