Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
DNA polymerase epsilon (Pol ε) is responsible for leading strand synthesis during DNA replication. Here the authors use Cryo-EM to describe the architecture of the Pol ε holoenzyme and to provide an atomic model for the leading strand replisome.
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Autores principales: | Zuanning Yuan, Roxana Georgescu, Grant D. Schauer, Michael E. O’Donnell, Huilin Li |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/bf5369f5dc0e4ac5973ac7d20dc7daaf |
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