Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries
Abstract Genome-wide CRISPR-based knockout (CRISPR-KO) screening is an emerging technique which enables systematic genetic analysis of a cellular or molecular phenotype in question. Continuous improvements, such as modifications to the guide RNA (gRNA) scaffold and the development of gRNA on-target...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/bf61f265b7c34397b4f245df7adcb64e |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|