Structural determinants and functional consequences of protein affinity for membrane rafts

Lipid rafts are plasma membrane domains that specifically recruit particular proteins. Here, the authors show that the surface area, length and palmitoylation of single-pass transmembrane domains are crucial for raft partitioning and propose a general model to predict protein association with rafts.

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Autores principales: Joseph H. Lorent, Blanca Diaz-Rohrer, Xubo Lin, Kevin Spring, Alemayehu A. Gorfe, Kandice R. Levental, Ilya Levental
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/bf79ee15bd4e4f5e84037c1d3629d8d3
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