Structural determinants and functional consequences of protein affinity for membrane rafts
Lipid rafts are plasma membrane domains that specifically recruit particular proteins. Here, the authors show that the surface area, length and palmitoylation of single-pass transmembrane domains are crucial for raft partitioning and propose a general model to predict protein association with rafts.
Guardado en:
Autores principales: | Joseph H. Lorent, Blanca Diaz-Rohrer, Xubo Lin, Kevin Spring, Alemayehu A. Gorfe, Kandice R. Levental, Ilya Levental |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/bf79ee15bd4e4f5e84037c1d3629d8d3 |
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