Perspectives for the reconstruction of 3D chromatin conformation using single cell Hi-C data.
Construction of chromosomes 3D models based on single cell Hi-C data constitute an important challenge. We present a reconstruction approach, DPDchrom, that incorporates basic knowledge whether the reconstructed conformation should be coil-like or globular and spring relaxation at contact sites. In...
Saved in:
Main Authors: | , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/bf9ef8a3ca1c4ad0bd894ed8ee553a32 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!