Novel Vaginal Microflora Colonization Model Providing New Insight into Microbicide Mechanism of Action

ABSTRACT Several broad-spectrum microbicides, including cellulose sulfate (CS), have passed conventional preclinical and phase I clinical safety evaluation and yet have failed to protect women from acquiring HIV-1 in phase II/III trials. Concerns have been raised that current preclinical algorithms...

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Autores principales: Raina N. Fichorova, Hidemi S. Yamamoto, Mary L. Delaney, Andrew B. Onderdonk, Gustavo F. Doncel
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/c02cf8723ae24c2f9533b469c83e2261
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