Novel Vaginal Microflora Colonization Model Providing New Insight into Microbicide Mechanism of Action
ABSTRACT Several broad-spectrum microbicides, including cellulose sulfate (CS), have passed conventional preclinical and phase I clinical safety evaluation and yet have failed to protect women from acquiring HIV-1 in phase II/III trials. Concerns have been raised that current preclinical algorithms...
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Auteurs principaux: | Raina N. Fichorova, Hidemi S. Yamamoto, Mary L. Delaney, Andrew B. Onderdonk, Gustavo F. Doncel |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2011
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Accès en ligne: | https://doaj.org/article/c02cf8723ae24c2f9533b469c83e2261 |
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